中国农业科学院陈刚导师主页

1．       Dan Zhu, Biniam Kebede, Kiri McComb, Alan Hayman, Gang Chen*, Russell Frew*. Milk biomarkers in relation to inherent and external factors based on metabolomics. Trends in Food Science & Technology. 2021, 109, 51–64.

2．       Dongfei Tan, Aijin Ma, Shaolei Wang, Qingyang Zhang, Man Jia, Afaf Kamal-Eldin, Huaxing Wu*, and Gang Chen*. Effects of the Oxygen Content and Light Intensity on Milk Photooxidation Using Untargeted Metabolomic Analysis. Journal of Agricultural and Food Chemistry. 2021, 69, 26, 7488-7497.

3．       Dongfei Tan, Xia Zhang, Meicheng Su, Man Jia, Dan Zhu, Biniam Kebede, Huaxing Wu*, Gang Chen*. Establishing an untargeted-to-MRM liquid-chromatography-mass spectrometry method for discriminating reconstituted milk from ultra-high temperature milk. Food Chemistry 337 (2021) 127946

4．       Jing Cui, Dan Zhu, Meicheng Su, Dongfei Tan, Xia Zhang, Man Jia, Huaxing Wu, Gang Chen*. Lipidomics Strategy for the Identification of Ultra-High Temperature and Reconstituted Milk by UPLC-Q-Exactive Orbitrap Mass Spectrometry. Food Analytical Methods. 2021, 14(5), 1064-1073. 

5．       Xia Zhang, Min Gan, Jingyun Li, Hui Li, Meicheng Su, Dongfei Tan, Shaolei Wang, Man Jia, Liguo Zhang* and Gang Chen*. An Endogenous Indole Pyruvate Pathway for Tryptophan Metabolism Mediated by IL4I1. Journal of Agricultural and Food Chemistry, 2020, 68, 10678−10684

6．      Meicheng Su, Yongyou Cheng, Congcong Zhang, Dan Zhu, Man Jia, Qingyang Zhang, Huaxing Wu, Gang Chen*. Determination of the levels of tryptophan and twelve metabolites in milk by high-performance liquid chromatography-tandem mass spectrometry with the QuEChERS method. Journal of Dairy Science, 2020, 103:9851-9859

7．       Min Gan, Hongbiao Ding*, Gang Chen*. 6-Formylindolo[3,2-b]carbazole reduces apoptosis induced by benzo[a]pyrene in a mitochondrial-dependent manner. Cell Biology International, 2020, DOI: 10.1002/cbin.11450

8．    Jing Cui, Dan Zhu, Meicheng Su, Dongfei Tan, Xia Zhang, Man Jia, Gang Chen*.  The combined use of 1H and 2D NMR-based metabolomics and chemometrics for non-targeted screening of biomarkers and identification of reconstituted milk. Journal of the Science of Food and Agricultural. 2019 99:6455-6461.

9．    Congcong Zhang, Jian Hu, Fengmei Sun, Man Jia, Gang Chen*, Cuiling Wu, Lufei Zheng*. Determination of four main components of gentamicin in animal tissues after solid phase extraction by high performance liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 2018 Oct 30;32(20):1766-1772.   

10．   Qiangqiang Li#, Yan Zhao#, Dan Zhu, Xiumei Pang, Yue Liu, Russell Frew, Gang Chen*. Lipidomics profiling of goat milk, soymilk and bovine milk by UPLC-Q-Exactive Orbitrap Mass Spectrometry. Food Chemistry, 2017, 224:302-309.

11．   Qiangqiang Li, Zunbo Yu, Dan Zhu, Xianghe Meng, Xiumei Pang, Yue Liu, Russell Frew, He Chen*, Gang Chen*. The application of NMR-based milk metabonomics in milk authenticity identification. Journal of the Science of Food and Agricultural, 2017, 97(9):2875-2882.

12．   Dan Zhu, Qiangqiang Li, Xiumei Pang, Xue Wang, Yue Liu, Gang Chen*. 2016. A Sensitive Electrochemical Impedance Immunosensor for Determination of Malachite Green and Leucomalachite Green in the Aqueous Environment [J]. Analytical and Bioanalytical Chemistry, 408(20): 5593-5600.

13．   Dan Zhu, Yang Mu, Qiangqiang Li, Xiumei Pang, Xue Wang, Yue Liu, Gang Chen*. 2016. A novel method for artificial antigen synthesis and preparation of a polyclonal antibody for the sensitive determination of leucomalachite green in fish samples by enzyme-linked immunoassay. Analytical Method 8 (32), 6236-6243.

14．   Dan Zhu, Qiangqiang Li, Kevin C. Honeychurch, Martina Piano, Gang Chen*. 2016. Determination of Malachite Green in Aquaculture Water by Adsorptive Stripping Voltammetry. Analytical Letters, 49(9): 1436-1451.

15．   Dan Zhu, Qiangqiang Li, Xiumei Pang, Yuwei Yuan, Gang Chen*.2016. Electrochemical behavior of isometamidium and its determination in milk samples at a SWCNT-AuNPs-modified glassy carbon electrode. Food Analytical Methods, 9:1963–1969.

16．   Qiangqiang Li, Xianghe Meng, Dan Zhu, Xiumei Pang, Kaiqiang Wang, Russell Frew, Gang Chen*. Determination of Non-protein Nitrogen Adulteration in Milk by Nuclear Magnetic Resonance. Analytical Letters, 2016, 49(18):1–11.

17．   Xiaoxia Mi, Sicong Li, Yanhua Li, KaiqiangWang, Dan Zhu, Gang Chen*. 2014. Quantitative determination of 26 steroids in eggs from various species using liquid chromatography–triple quadrupole-mass spectrometry. Journal of Chromatography A. 1356: 54–63.

18．   Gang Chen, Ying Bai, Li Ren, Dan Zhu, Yanhua Li, Meiying Fang, Huda Al-Kateb, Olena Doran. 2015. Metabolism of androstenone, 17b-estradiol and dihydrotestosterone in primary cultured pig hepatocytes and the role of 3b-hydroxysteroid dehydrogenase in this process. PLOS ONE Volume 10 (Issue 1) e113194.

19．   Chen Chen, Xiaoxia Mi, Yuwei Yuan, Gang Chen*, Li Ren, Kaiqiang Wang, Dan Zhu, Yongzhong Qian. 2014. A preliminary risk assessment of potential exposure to naturally occurring estrogens from Beijing (China) market milk products. Food and Chemical Toxicology 71: 74–80.

20．   Yinan Du, Sicong Li, Xiaoxia Mi, Xiaochun Zheng, Gang Chen*. 2014. The electrochemical behavior of Sudan I and Sudan II at graphene modified electrodes. Asian J. Chem. 26(4), pp 951-954.

21．   Xiaochun Zheng, Xiaoxia Mi, Sicong Li, Gang Chen*. 2013. Determination of Xylazine and 2,6-Xylidine in Animal Tissues by Liquid Chromatography - Tandem Mass Spectrometry. J. Food Sci. 78(6): T955-T959.

22．   Gang Chen, Sicong Li, Xinxing Dong, Ying Bai, Ailiang Chen, Shuming Yang, Meiying Fang, Galia Zamaratskaia, Olena Doran. 2012 Investigation of testosterone, androstenone, and estradiol metabolism in HepG2 cells and primary culture pig hepatocytes and their effects on 17βHSD7 gene expression. PLOS ONE Volume 7 (Issue 12) e52255.

23．   Chen Gang, Ren, L., Yang, S.M., Qiu, J., Kamal-Eldin, A., Lundström, K. 2010 Determination of androstenone levels in porcine plasma by LC-MS/MS. Food Chem. 122 1278–1282.

24．   Dong X., Bai Y., Xin Y., Xu Q., Chen Gang*, Fang M. 2012 Investigation on the transcription factors of porcine 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase genes. Gene 499: 186–190.

25．   Chen Gang, Cue, R.-A., Lundstrom, K., Wood, J.D. & Doran, O. 2008. Regulation of cytochrome P450 2A6 protein expression by skatole, indole and testicular steroids in primary cultured pig hepatocytes. Drug Metab Dispos 36(1): 56–60.

26．   Chen Gang, Zamaratskaia, G., Andersson, H. K. & Lundström, K. 2007. Effects of raw potato starch and live weight on fat and plasma skatole, indole and androstenone levels measured by different methods in entire male pigs. Food Chem 101, 439–448.

27．   Chen Gang, Bourneuf, E., Marklund, S., Zamaratskaia, G., Madej, A. & Lundström,   K. 2007. Gene expression of 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase in relation to androstenone, testosterone, and estrone sulphate in gonadally-intact male and castrated pigs. J Anim Sci 85, 2457–2463.

28．   Chen Gang, Zamaratskaia, G., Madej, A. & Lundström, K. 2006. Effect of hCG administration of the levels of androstenone, skatole and indole in entire male pigs. Meat Sci 72, 339–347.

第一发明人专利和软件著作权                                  

1.          鉴别复原乳和超高温灭菌乳的方法，授权号ZL201910838179.0

2.          一种鉴别超高温灭菌乳与复原乳的核磁共振波谱方法，授权号ZL201811308253.X

3.          一种鉴别奶品品质的方法，授权号ZL 201510432183.9

4.          一种隐性孔雀石绿半抗原的制备方法，授权号ZL 201410854438.6

5.          牛奶中雌激素的定量检测方法，授权号ZL 2012 1 0028917.3

6.          牛奶中主要兽药残留核磁数据库软件V1.0，软件著作权，证书号：软著登字第6134078号。登记号：2020SR1255382

7.          食品中主要兽药残留标准品核磁数据库软件V1.0，软件著作权，证书号：软著登字第6134096号。登记号：2020SR1255400

第一完成人标准                                                  

1.          食品安全国家标准《动物性食品中赛拉嗪及代谢物2,6-二甲基苯胺残留量的测定 液相色谱-串联质谱法》。

2.          农业行业标准《饲料中赛地卡霉素的测定 液相色谱-串联质谱法》（农业部公告第316号-7-2020）。

3.          农业行业标准《饲料中他唑巴坦的测定 液相色谱-串联质谱法》（农业部公告第316号-8-2020）。

4.          农业行业标准《饲料中赛地卡霉素的测定 高效液相色谱法》（农业部2224号公告-1-2015）。